Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients.

Faculty of Dental Medicine for Girls

Status: Active, not recruiting

Conditions: Orthodontic Tooth Movement; Periodontal Diseases; Cancer Metastatic

Treatments: Device: Biolase ;Low Level Laser

Study type: Interventional

Funder types: Other

Identifiers

NCT05739838

ORTHO-108-6-J

Details and patient eligibility

About

To investigate the effect of Low Level Laser therapy on orthodontic tooth movement of periodontally compromised patients by evaluating the rate of orthodontic tooth movement and the level of Osteocalcin in the gingival crevicular fluid.

Full description

Low-Level laser therapy has been reported as an effective adjunct to non surgical periodontal treatment for inflammation control and tissue reparation in patients with periodontitis. Previous studies have shown that application of low-level laser therapy reduced pocket depth and decreased the inflammatory process through regulatory control of inflammatory cytokines level, therefore this study will investigate the effect of low-level laser on the periodontal tissue .Accelerating orthodontic tooth movement is one of the primary demand in orthodontics to prevent side effects as root resorption, caries and decreased patient compliance . Numerous researchers have also studied the use of LLLT in accelerating orthodontic tooth movement and have considered the laser to be effective while others achieved the opposite . Hence, This study is aiming to investigate the effects of LLLT in accelerating tooth movement.

Enrollment: 20 patients

Sex: All

Ages: 25 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• No systemic disease.
• No history medication (antibiotics and/or anti inflammatory) in the previous 4 months.
• Self motivated patients with acceptable oral hygien.

Exclusion criteria

• Previous orthodontic treatment
• Aggressive periodontitis
• Smokers
• pregnant patients

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20 participants in 2 patient groups

Periodontally compromised patients subjected to low level laser therapy

Experimental group

Description:

periodontally compromised patients with pocket depth of more than 5 mm before receiving nonsurgical periodontal treatment treatment or/and pocket depth of less than 4 mm with periodontal status identified as stable for at least 3 month after nonsurgical periodontal treatment subjected to low-level laser of 940 nm will be applied at day one after start of treatment , weekly during the first month, then monthly.

Treatment:

Device: Biolase ;Low Level Laser

Periodontally compromised patients

No Intervention group

Description:

periodontally compromised patients with pocket depth of more than 5 mm before receiving nonsurgical periodontal treatment treatment or/and pocket depth of less than 4 mm with periodontal status identified as stable for at least 3 month after nonsurgical periodontal treatment.