Low Level Laser Therapy Applied in Orthodontic Tooth Movement

China Medical University

Status and phase: Completed; Early Phase 1

Conditions: Orthodontic Appliance Complication

Treatments: Device: Low Level Laser Therapy; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT05695053

CMUH110-REC2-138

Details and patient eligibility

About

Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time. Low Level Laser Therapy(LLLT) applied in Orthodontic Tooth Movement, which stimulates formation of osteoclast-like cells expression in vitro. Osteoclast can be served as an index for tooth movement. Increasing the number of osteoclast will increase bone formation and tooth movement. We plan to find a useful clinical protocol to improve the efficiency of orthodontic tooth movement. Test low energy laser in vitro. Find an effective wavelength and irradiation time to stimulate formation of osteoclast. Develop an useful protocol that clinical orthodontist could follow and reduce orthodontic treatment time.

Enrollment: 20 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with good oral hygiene
• 18 years old
• Patients who required bilateral canine retraction into the extracted premolar

Exclusion criteria

• Serious medical history
• Poor oral hygiene
• Previous orthodontic treatment
• Orthognathic surgery or syndromic patients

Trial design

Primary purpose: Device Feasibility

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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20 participants in 2 patient groups, including a placebo group

with LLLT

Experimental group

Treatment:

Device: Low Level Laser Therapy

without LLLT

Placebo Comparator group

Treatment:

Other: Placebo