Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy.

Nazmy Edward Seif

Status: Enrolling

Conditions: Laparoscopic; Epidural; Nephrectomy; Anesthesia

Treatments: Procedure: Low-Thoracic Epidural Anesthesia; Procedure: General Anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT04546230

LTEALN

Details and patient eligibility

About

Laparoscopic nephrectomy is a surgical technique to excise a diseased kidney. It's a minimally invasive technique, so when compared to open surgery, it can mean significantly less post-operative pain, shorter hospital stay, earlier return to work and daily life activities, a more favourable cosmetic result and outcomes similar to that of open surgery.

Recently, advanced laparoscopic surgery has targeted older and high risk patients for general anesthesia; in these patients, regional anesthesia offers several advantages with improved patient satisfaction. Compared with alternative anesthetic techniques, epidural anesthesia may reduce the risks of venous thromboembolism, myocardial infarction, bleeding complications, pneumonia, respiratory depression and renal failure.

The aim of this study is to compare the conventional general anesthetic technique to the regional anesthesia for laparoscopic nephrectomy, in modified lateral decubitus position using low-pressure pneumoperitoneum.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I - II.
• Adult patients scheduled for laparoscopic nephrectomy.

Exclusion criteria

• Patient refusal.
• Contraindication to regional anesthesia (e.g., coagulopathy, site infection).
• Allergy to local anesthetics.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups

E group

Experimental group

Description:

Low-Thoracic Epidural Anesthesia

Treatment:

Procedure: Low-Thoracic Epidural Anesthesia

G group

Active Comparator group

Description:

General Anesthesia

Treatment:

Procedure: General Anesthesia