Lower Extremity Elevation to Minimize Hemodynamic Instability During Induction of General Anesthesia

The University of Texas System (UT)

Status: Enrolling

Conditions: Post Induction Hypotension

Treatments: Procedure: Group 1: LEE

Study type: Interventional

Funder types: Other

Identifiers

NCT06513169

HSC-MS-22-0145

Details and patient eligibility

About

The purpose of this study is to determine if lower extremity elevation (LEE) will reduce the incidence of postinduction hypotension, to compare the utilization of vasoactive medications after induction in patients with LEE and patients without LEE and to determine if LEE will increase measured cardiac output

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists (ASA)3 or lower
• Patients requiring general anesthesia

Exclusion criteria

• Allergic reaction to drugs commonly used for general anesthesia including fentanyl, midazolam, propofol, ephedrine and phenylephrine
• Pregnant women
• Requiring rapid sequence induction
• Prisoners
• Patient refusal
• Emergency Surgery

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 2 patient groups

Group 1: LEE

Experimental group

Treatment:

Procedure: Group 1: LEE

Group 2: no LEE

No Intervention group