Lower Extremity Muscle and Function in the Elderly: Study 2

Tufts University

Status: Completed

Conditions: Mobility Limitation

Treatments: Behavioral: Low velocity high force Power Training; Behavioral: High velocity low force Power Training

Study type: Interventional

Funder types: Other

Identifiers

NCT01614392

AG-18844

Details and patient eligibility

About

This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.

Enrollment: 52 patients

Sex: All

Ages: 70 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male and Female 70-85 yrs
• Community dwelling
• Short Performance Battery Score >9
• BMI range 19-32 kg/m2
• Willingness to be randomized and come the laboratory for 20 weeks.

Exclusion criteria

• Acute or Terminal Illness
• MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
• Upper or Lower extremity fracture in previous 6 months
• Uncontrolled hypertension (150/90mmHg)
• Neuromuscular diseases and drugs that affect neuromuscular function
• Hormone replacement therapy
• Participation in any regular endurance or resistance training exercise during previous 3 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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52 participants in 2 patient groups

High velocity low force Power Training

Experimental group

Description:

Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Treatment:

Behavioral: High velocity low force Power Training

Low velocity high force Power Training

Experimental group

Description:

Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Treatment:

Behavioral: Low velocity high force Power Training