Lower-Limb Muscle Mass and Balance Performance (LMBP)

Bursa Uludag University

Status: Not yet enrolling

Conditions: Lower-limb Muscle Mass and Balance Performance

Study type: Observational

Funder types: Other

Identifiers

NCT07365605

E-87914409-050.04-117156

Details and patient eligibility

About

This study will examine the interaction between lower-limb muscle mass and balance performance in moderately physically active young men. Body composition parameters, including appendicular skeletal muscle mass, leg muscle mass, and the ratio of lower-limb muscle mass to body weight (LMM/BW), will be assessed using bioelectrical impedance analysis. Balance performance will be evaluated using a center-of-pressure-based static balance test, with classifications derived from sway path length and sway area parameters.

Participants will be grouped according to balance performance metrics, and muscle mass indicators will be compared between balance-based groups. Correlation analyses will also be conducted to explore associations between muscle mass variables and balance outcomes across the entire sample. It is anticipated that normalized muscle mass indicators, particularly LMM/BW, will demonstrate greater discriminative sensitivity than absolute muscle mass measures in relation to balance performance. The findings are expected to contribute to a more precise understanding of how relative lower-limb muscular capacity relates to postural control in young, physically active populations.

Full description

This study will employ a cross-sectional observational design to investigate the relationship between lower-limb muscle mass and balance performance in moderately physically active young men. The primary focus will be to determine whether normalized muscle mass indicators, particularly the ratio of lower-limb muscle mass to body weight (LMM/BW), demonstrate greater sensitivity in explaining balance-performance differences than absolute muscle mass measures.

A cohort of healthy male participants aged 20-30 years will be recruited. All participants will be moderately physically active and free from musculoskeletal injuries, neurological disorders, or medical conditions that could affect balance performance. After providing written informed consent, participants will undergo standardized anthropometric and body composition assessments using bioelectrical impedance analysis to obtain appendicular skeletal muscle mass, leg muscle mass, total muscle mass, body fat percentage, and LMM/BW.

Balance performance will be evaluated using a center-of-pressure-based static balance test performed on a stabilometric platform. Participants will complete a 30-second quiet standing task, during which sway path length and sway area will be recorded as primary balance outcomes. These parameters will be used to classify participants into balance-performance-based groups in order to examine the discriminative capacity of different balance metrics with respect to muscle mass variables.

Between-group comparisons of muscle mass indicators will be conducted to identify differences associated with balance performance classifications. In addition, correlation analyses will be performed across the entire sample to assess the strength and direction of associations between muscle mass variables and balance outcomes. Effect size estimates will be calculated to support the interpretation of observed differences.

The study is expected to clarify whether relative lower-limb muscular capacity provides a more functionally meaningful explanation of balance performance than absolute muscle mass in young, physically active populations. The findings may contribute to improved methodological approaches in balance assessment and support the use of normalized muscle mass indicators in sports science, exercise physiology, and preventive health contexts.

Enrollment: 150 estimated patients

Sex: Male

Ages: 20 to 32 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Inclusion criteria required that participants (i) were between 20 and 30 years of age; (ii) had no lower-limb injuries that could affect test performance; (iii) were moderately physically active; and (iv) had not used ergogenic aids or stimulant substances for at least six months prior to the study.

Exclusion criteria

• Exclusion criteria included the presence of back, neck, leg, foot, or upper-limb pain within the previous six months, as well as a history of major orthopedic surgery involving the lower extremities or trunk.

Trial design

150 participants in 2 patient groups

Lower Balance Performance Group (LBP)

Description:

This cohort will include moderately physically active young men who exhibit higher sway path length values during a 30-second center-of-pressure-based static balance test, indicating lower balance performance. Participants in this group will have no musculoskeletal, neurological, or medical conditions affecting postural control. This cohort will be used to examine muscle mass characteristics associated with relatively poorer balance performance.

Higher Balance Performance Group (HBP)

Description:

This cohort will include moderately physically active young men who exhibit lower sway path length values during a 30-second center-of-pressure-based static balance test, indicating higher balance performance. Participants in this group will be free from conditions that may influence balance outcomes. This cohort will be used to evaluate muscle mass characteristics associated with relatively better balance performance.