LOXL1 Polymorphism in Pseudoexfoliation Syndrome

Samsung Medical Center

Status: Unknown

Conditions: Pseudoexfoliation Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT01515735

2011-06-035

Details and patient eligibility

About

To evaluate the association profiles of the lysyl oxidase-like 1 gene polymorphisms with pseudoexfoliation syndrome in the Korean population, Genotypes of lysyl oxidase-like 1 gene were analyzed by direct sequencing.

Full description

To evaluate the association profiles of the lysyl oxidase-like 1 gene polymorphisms with pseudoexfoliation syndrome in the Korean population, peripheral blood sampling will be done from the patients with pseudoexfoliation.

And genotypes of the three single nucleotide polymorphisms of lysyl oxidase-like 1 gene , rs1048661, rs3825942, rs2165241 were analyzed by direct sequencing.

Enrollment: 60 estimated patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Pseudoexfoliation

Exclusion criteria

• medical condition that peripheral blood sampling cannot be done

Trial design

60 participants in 1 patient group

pseudoexfoliation

Description:

The study group composted of the patients with pseudoexfoliation syndrome