LUNG FIBROTIC CHANGES ASSOCIATED WITH SARS-CoV-2 INFECTION (INC-CVD-202001)

Fundación para la Investigación del Hospital Clínico de Valencia

Status: Unknown

Conditions: Pulmonary Fibrosis

Study type: Observational

Funder types: Other

Identifiers

NCT04409275

INC-CVD-2020-01

Details and patient eligibility

About

Prospective, observational, multicenter study that will evaluate the changes in lung function that patients admitted with SARS-CoV-2 pneumonia will present according to the level of severity at 4, 12, 26 and 52 weeks after hospital discharge.

Full description

The project consists of a prospective, observational, multicenter study that will evaluate changes in lung function (forced spirometry, measurement of static lung volumes using plethysmography and pulmonary carbon monoxide diffusion test) that patients admitted with pneumonia will present. caused by SARS-CoV-2 according to the level of severity at 4, 12, 26 and 52 weeks after discharge from hospital. Restrictive pulmonary abnormalities will be confirmed by imaging tests (high resolution chest CT).

Enrollment: 500 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients admitted for bilateral pneumonia caused by SARS-CoV-2 (confirmed by PCR).
• Age over 18 years.
• Acceptance of informed consent.
• Life expectancy over 1 year.

Exclusion criteria

• Patients with a previous diagnosis of interstitial lung disease.
• Inability to attend review visits.