Lung Function in Post-COVID-19 Nursing Home Residents

University of Vic - Central University of Catalonia

Status: Completed

Conditions: Post-COVID-19 Syndrome

Treatments: Other: Previous exposure to SARS-CoV-2

Study type: Observational

Funder types: Other

Identifiers

NCT05866211

LUNGFUNCTIONCFCR101

Details and patient eligibility

About

The coronavirus disease 2019 (COVID-19) took a toll in institutionalised older adults, who represent a vulnerable population in European countries.

The aim of this study is to identify the predictive factors that worsens lung function in post-COVID nursing home (NH) residents.

This is a multicenter case-control study in nursing homes of Osona (Catalonia), where individuals with worsened (cases) and normal (controls) lung function will be studied. The inclusion criteria are: female and male from 65 to 95 years old, preserved cognitive capacity and positive diagnosis of COVID-19 at least 3 months prior.

We will assess sociodemographic variables, lung function [spirometry], fatigue [Chalder Fatigue Scale], frailty [Clinical Frailty Scale], and activities of daily living (ADL) [modified Barthel index].

Enrollment: 184 patients

Sex: All

Ages: 65 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• male and female
• preserved cognitive function
• previous positive diagnosis of COVID-19 at a minimum of 3 months to the day of data collection
• individuals living permanently in a nursing home

Exclusion criteria

• individuals in coma or palliative care
• any contraindication to perform spirometry (severe hypertension, myocardial infarction in the past week, non compensated heart failure, etc).

Trial design

184 participants in 2 patient groups

Case

Description:

Individuals with impaired lung function, according to spirometry results (FVC ≤ LLN and FEV1/FVC ≥ LLN).

Treatment:

Other: Previous exposure to SARS-CoV-2

Control

Description:

Individuals with normal lung function

Treatment:

Other: Previous exposure to SARS-CoV-2