Lung Health After Tuberculosis: Clinical and Functional Assessment in Post Pulmonary Tuberculosis Egyptian Patients.

Assiut University

Status: Completed

Conditions: Pulmonary Function; Newborn, Abnormal; Pulmonary Tuberculoses

Treatments: Diagnostic Test: spirometry

Study type: Observational

Funder types: Other

Identifiers

NCT05097638

5884

Details and patient eligibility

About

Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment

Full description

Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment which may influence their quality of life. However, the pattern and nature of post-tuberculosis lung impairment is still not identified. Thus, the aim of this study was to determine the type and degree of lung physiology changes in previously treated tuberculous patients which latter may affect their quality of life; thus helping clinicians for early diagnosis of lung impairment, especially in tuberculous endemic areas.

Enrollment: 210 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient completed an outpatient course of standard first line anti-tuberculosis therapy and declared as cured

Exclusion criteria

• Smoker (to avoid spirometry biases).
• Extrapulmonary tuberculosis cases
• Multidrug resistant tuberculosis
• known contraindications to spirometry testing
• Individuals with chest wall deformities or neuromuscular diseases
• Patients who failed to achieve acceptability and reproducibility criteria of the spirometry test
• Defaulter cases or irregular treatment,
• known coexisting chronic lung disease as history of asthma or interstitial lung diseases
• A history of illicit drug use
• Patients with comorbidities: renal and hepatic insufficiency, heart diseases and metabolic disorders.

Trial design

210 participants in 1 patient group

Cured pulmonary Tuberculosis patients

Description:

6 months after a completed course of anti-tuberculosis therapy

Treatment:

Diagnostic Test: spirometry