Lung Recruitment Maneuver for Predicting Fluid Responsiveness in Children

Seoul National University

Status: Completed

Conditions: Hypovolemia

Treatments: Diagnostic Test: lung recruitment maneuver

Study type: Interventional

Funder types: Other

Identifiers

NCT03184961

H1704-042-836

Details and patient eligibility

About

Lung recruitment maneuver induces a decrease in stroke volume, which is more pronounced in hypovolemic patients. The authors hypothesized that the changes of dynamic variables through lung recruitment maneuver could predict preload responsiveness in pediatric patients with lung protective ventilation

Enrollment: 30 patients

Sex: All

Ages: Under 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pediatric patients undergoing general anesthesia under 6 years old

Exclusion criteria

• arrhythmia
• <30%, ejection fraction
• lung disease

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

lung recruitment maneuver

Experimental group

Description:

Heart rate, mean arterial pressure, stroke volume, pulse pressure variations, pleth variability index, and photoplethysmographic waveform were recorded before lung recruitment maneuver (application of continuous positive airway pressure of 25 cm H2O for 20 s), during lung recruitment maneuver when stroke volume reached its minimal value. Cardiac index measured before and after volume expansion (10ml/kg saline, 0.9%, infused during 10 min). Patients were considered as responders to fluid administration if cardiac index increased greater than or equal to 15%.

Treatment:

Diagnostic Test: lung recruitment maneuver