Lung Screening in People Cured of Hodgkin Lymphoma

The Christie NHS Foundation Trust

Status: Completed

Conditions: Hodgkin Lymphoma; Lung Cancer

Treatments: Diagnostic Test: Low dose CT thorax

Study type: Interventional

Funder types: Other

Identifiers

NCT04986189

CFTSp204

Details and patient eligibility

About

A single site non-commercial study in which people treated for Hodgkin lymphoma survivors will be invited to have a single low dose CT of thorax for lung cancer screening

Enrollment: 102 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 18-80
• 5 year or more survivor of HL
• Any of: a) treated with radiotherapy for HL with radiation dose to the lung b) an alkylating agent containing chemotherapy regimen known to increase lung cancer risk
• Living within approximately 40 miles of The Christie Hospital

Exclusion criteria

• Previous diagnoses of malignant neoplasm of trachea, bronchus, lung, thymus or pleura
• A current diagnosis of metastatic cancer
• Residents in nursing homes or housebound
• Had a CT scan of the thorax within the last 12 months
• Pregnant women
• Unable to provide consent

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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102 participants in 1 patient group

Invitation to have a low dose CT thorax

Other group

Description:

All participants are invited to undergo a low dose CT thorax

Treatment:

Diagnostic Test: Low dose CT thorax