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Lung Ultrasound, Cholecystectomy, Atelectasis

I

Istanbul Medeniyet University

Status

Completed

Conditions

Laparoscopic Cholecystectomy

Treatments

Procedure: peep 5
Procedure: peep 10

Study type

Interventional

Funder types

Other

Identifiers

NCT06664658
IRB: Approval No. 2022/0257

Details and patient eligibility

About

Atelectasis is an important complication that can be seen during general anesthesia, especially in patients with lung problems and in patients having pneumoperitoneum. Application of PEEP during anesthesia may reduce the incidence of atelectasis.Lung ultrasonography is a tool that is easily accessible, can be applied at the bedside, is non-invasive, does not cause radiation exposure, and is increasingly used in daily practice in operating rooms. In this study, it was aimed to evaluate the occurrence of atelectasis by using lung ultrasound, and to investigate the effectiveness of ultrasound in determining the risk of developing atelectasis in patients ventilated with different PEEP values during general anesthesia. The study was conducted in 60 patients aged 18 and over, from ASA I-III groups, who were planned to undergo laparoscopic cholecystectomy surgery at the Istanbul Medeniyet University Göztepe Training and Research Hospital General Surgery Clinic, and their written and verbal informed consents were obtained. The patients included in the study were divided into 2 groups. Among the patients who were going to be operated, 5 PEEP were applied to Group I (n=30) cases, and 10 PEEP to Group II (n=30) cases during ventilation with anesthesia device. All patients were evaluated by transthoracic lung ultrasonography before anesthetic induction, after tracheal intubation, after pneumoperitoneum, and 15 minutes after recovery from anesthesia. According to the lung USG protocol, a total of 6 regions, including 2 quadrants of each hemi-thorax anterior wall, 2 right and left lateral walls, and 2 quadrants of the posterior wall, a total of 12 regions in each patient were scanned, and the images were evaluated. According to the modified lung USG scoring system, each region was scored between 0-3 consistent with the degree of atelectasis. The total score was calculated for each patient. Hemodynamic follow-up of the patients was performed. Anesthesia times, surgery times, and pneumoperitoneum times were recorded and compared.

Enrollment

60 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients are aged 18 and over, from ASA I-III groups, who were planned to undergo laparoscopic cholecystectomy surgery

Exclusion criteria

  • Patients who do not give consent
  • Patients who have previously undergone thoracic surgery
  • Patients with a body mass index > 40 kg/m²
  • Patients with severe COPD
  • Patients with serious pulmonary diseases
  • Patients diagnosed with obstructive sleep apnea syndrome
  • ASA IV patients
  • Patients with advanced cardiac and neurological diseases
  • Patients with mental retardation and limited cooperation
  • Patients who terminate their participation in the study for any reason during the trial
  • Pediatric age group Pregnant women

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

60 participants in 2 patient groups

PEEP 5
Active Comparator group
Description:
Patients are in the group undergoing PEEP 5 cm h2o during surgery
Treatment:
Procedure: peep 5
peep 10
Active Comparator group
Description:
Patients are in the group undergoing PEEP 10 cm h2o during surgery
Treatment:
Procedure: peep 10

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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