Lung Ultrasound in Neonatal Intensive Care Units

Assiut University

Status: Not yet enrolling

Conditions: Neonatal Respiratory Distress

Treatments: Device: Ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT06372951

Lung ultrasound in neonate

Details and patient eligibility

About

Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .

Full description

• Lung disease is the most common cause of neonatal respiratory distress.

• It can result in respiratory failure and death in severe cases.

• The mortality rate is approximately 11%:32%.

• Identification of the etiology of lung disease is important for neonatologists.

• Traditionally, chest X-ray has been considered as the most valuable imaging modality for the diagnosis of lung diseases, but it unavoidably causes radiation damage to the patient.

• Neonates are susceptible to radiation because they have rapidly dividing cells that cannot repair mutated DNA.

• The risk of cancer induction in infants receiving a single small dose of radiation is 2-3 times higher than the average population and 6-9 times higher than the risk from an exposure of a 60-year-old patient.

• New imaging modalities have been introduced in clinical practice in recent years such as lung ultrasound.

• One of the most common causes of neonatal respiratory distress that can be diagnosed by ultrasound is :Respiratory Distress Syndrome:

  • Respiratory distress syndrome.. is a major cause of neonatal mortality.
  • It mainly occur in preterm infants due to structural and functional lung immaturity.
  • Pulmonary surfactant insufficiency is an important pathogenesis in respiratory distress syndrome.
  • The ultrasonic features of respiratory distress syndrome are: Compact B-Lines, white lung appearance, abnormality in pleural line (thick and irregular),lung consolidation.

• Lung ultrasound has the advantages of :

  • Non-ionizing.
  • Easy to operate.
  • Low coast.
  • Portable for bedside use.
  • The imaging is performed in real-time.

• Thus making it as a potential tool to be used in neonatal intensive care units.

Enrollment: 132 estimated patients

Sex: All

Ages: 1 to 28 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Neonates in neonatal intensive care units

Exclusion criteria

• Patients with poor-quality of lung ultrasound image.
• Subcutaneous emphysema.