Lung Ultrasound Score and Weaning Outcome

Cairo University (CU)

Status: Completed

Conditions: Lung Ultrasound Score; Acute Respiratory Failure

Treatments: Other: lung ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT05289960

MS-490-2020

Details and patient eligibility

About

Objectives: Failure of extubation of patients on mechanical ventilation is one of the common problems in the ICU.

Aim of work: To evaluate the validity of lung ultrasound score in prediction of weaning outcomes and post-extubation distress.

Full description

Methods: A prospective observational study of 50 patients planned for extubation who passed a spontaneous breathing trial, lung ultrasound score and serum level of NT-PRO BNP were done to all patients at end of spontaneous breathing trial, and all patients were followed after extubation and monitored for oxygenation, re-intubation rate, ICU stay, and ICU mortality.

Enrollment: 50 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Patients age > 18 years

2. Patients intubated and mechanically ventilated for more than 48 hours in the intensive care unit and planned for extubation.

Exclusion criteria

• 1. Patients < or =18 years 2. Patients with left ventricular failure

  2. Right ventricular failure

  3. Pulmonary hypertension

  4. Aortic valve disease

  5. Hyperthyroidism

  6. Tracheostomy

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

patients eligible for weaning by spontaneous breathing trial

Other group

Treatment:

Other: lung ultrasound

non invasive ventilation after weaning

Other group

Treatment:

Other: lung ultrasound