Lymph Node Metastases and Arterial Ligation in Rectal Cancer Surgery

Region Västmanland

Status: Completed

Conditions: Lymph Node Metastases

Study type: Observational

Funder types: Other

Identifiers

NCT03314961

Dnr2013/099

Details and patient eligibility

About

Lymph node status is of major prognostic importance in non-metastatic rectal cancer. For oncological reasons, central arterial ligation of the inferior mesenteric artery (IMA) is suggested. However, there is no conclusive evidence presented for this procedure.

This study aimed at investigating the localisation of lymph node metastases and the role of central versus peripheral arterial ligation of in rectal cancer specimens.

Full description

Prospective population-based study of specimens from patients that underwent surgical resection for rectal cancer in Västmanland County, Sweden. Specimens were divided in 3 sections (A-C) and the total amount of lymph nodes and the location of lymph node metastases were analysed.

Multivariate analysis was used to explore the relationship between lymph node counts and age, gender, BMI, preoperative oncological treatment, type of surgery, tumour stage, vessel and specimen length.

Enrollment: 151 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients that were curatively operated for rectal cancer in Västmanlands county 2012-2016.

Exclusion criteria

• Patients that were not operated or had another type of cancer.