Lymph Node Pathologic Grading Strategy

Fudan University

Status: Enrolling

Conditions: Lung Adenocarcinoma

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06745830

FUSCCLN1203

Details and patient eligibility

About

The percentage of high-grade patterns in metastatic LNs (mLNs) that can predict poor outcomes has yet to be determined. Additionally, the potential implications of other histologic patterns in metastatic lymph nodes on patient outcomes warrant further investigation.

We conducted a retrospective cohort study to investigate the prognostic value of pathologic pattern in metastatic lymph nodes.

Enrollment: 2,998 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

From January 2011 to September 2021, we consecutively collected patients with invasive LUAD who underwent surgical resection at the Department of Thoracic Surgery, Fudan University Shanghai Cancer Center.

Exclusion criteria

1. adenocarcinoma in situ, minimally invasive adenocarcinoma, invasive mucinous adenocarcinoma, and other variants of adenocarcinoma;
2. incomplete common driver mutation data;
3. unavailable pathologic slides.

Trial design

2,998 participants in 1 patient group

Invasive LUAD who underwent surgical resection

Treatment:

Other: No intervention