Lymph Node Ratio as a Predictor for Outcome in Rectal Cancer

Mansoura University

Status: Unknown

Conditions: Recurrence

Treatments: Procedure: Lymph node harvesting

Study type: Observational

Funder types: Other

Identifiers

NCT05221684

LN ratio in rectal cancer

Details and patient eligibility

About

This study aims to evaluate the value of the LNR as a prognostic indicator in patients with rectal cancer who offered total mesorectal excision.

Full description

Patients and methods Study design and setting This is a retrospective review of prospectively collected and maintained database of patients with CRC admitted in the Oncology Center of Mansoura University (OCMU), the Colorectal Surgery Unit of Mansoura University Hospitals, and the Department of General Surgery of Alexandria University.

Selection criteria Patients of either gender aged 18 years or above who presented with rectal cancer of any stage will be included in the study. We will exclude patients with patients younger than 18 years; patients with synchronous colon cancer; synchronous liver, pulmonary or bones metastasis; or synchronous gastrointestinal cancer; or patients who were lost to follow-up.

Study endpoints The primary endpoint of the study is to assess the value of lymph node ratio (LNR) on the oncological outcomes.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• rectal cancer of TNM stage I-III
• underwent radical resection with curative intent

Exclusion criteria

• synchronous colon cancer
• synchronous gastrointestinal cancer
• underwent palliative resection
• presented with intestinal obstruction
• those lost to follow-up.