Lymphatic System Reflux After Lymphatic Operation

Chang Gung Medical Foundation

Status: Completed

Conditions: Lymphedema

Treatments: Other: Veins with reflux; Other: Reflux-free recipient veins

Study type: Observational

Funder types: Other

Identifiers

NCT06249360

202301216B0

Details and patient eligibility

About

This study aimed to determine the impact on outcomes when recipient veins with reflux were used for LVA for the treatment of unilateral lower limb lymphedema.

Full description

The use of recipient veins with reflux for lymphaticovenous anastomosis (LVA) is discouraged because of the common belief that it may lead to venous-lymphatic reflux (VLR), a phenomenon in which venous blood is refluxed into the lymphatic lumen after anastomosis, which can lower the long-term patency rate. However, this concept has yet to be validated.

Enrollment: 79 patients

Sex: All

Ages: 20 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• This study including patients diagnosed with lymphatic-related diseases at Kaohsiung Chang Gung Memorial Hospital from October 1, 2015, to December 31, 2022.
• Patients who underwent LVA for unilateral lower-limb lymphedema.

Exclusion criteria

• Patients under the age of 20.
• Patients lost to follow-up or with incomplete data.

Trial design

79 participants in 1 patient group

Lower Limb Lymphedema

Description:

Patients with cancer-related unilateral lower limb lymphedema were enrolled.

Treatment:

Other: Reflux-free recipient veins

Other: Veins with reflux