Lymphocytes Subpopulation in Cancer Patients (CaLym)

DERSHENG SUN

Status: Unknown

Conditions: Cancer

Treatments: Other: lymphocyte

Study type: Interventional

Funder types: Other

Identifiers

NCT02516371

UC15OISI0093

Details and patient eligibility

About

This study aims to exam the subpopulation of lymphocytes and evaluate the clinico-pathologic correlations.

Full description

The host's inflammatory response in the tumor microenvironment could effect cancer progression and prognosis. As components of systemic inflammatory response, lymphocytes, neutrophils, and platelets are being recognised to have an important role in carcinogenesis and tumor progression. To date, a number of peripheral blood-derived inflammation-based scores such as the neutrophil-lymphocyte ratio (NLR), platelet- lymphocyte ratio (PLR) and so on have been proposed as prognostic markers in numerous types of cancers. But, very little is known of their impact in subpopulation of lymphocytes. The investigators try to evaluate the activity of lymphocytes in peripheral blood and find out the relationship among clinical prognosis.

Enrollment: 100 estimated patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. cancer patients of Uijeongbu St. Mary's Hospital
2. never treated with chemotherapy
3. Age between 20~80 years-

Exclusion criteria

1. treated with chemotherapy before
2. No informed consent form

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

lymphocytes

Other group

Description:

To evaluate the subpopulation of lymphocytes in cancer patients

Treatment:

Other: lymphocyte