Lymphoma in the Orbit

University of Zurich (UZH)

Status: Unknown

Conditions: Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma

Treatments: Procedure: Lymphoma-Biopsy

Study type: Observational

Funder types: Other

Identifiers

NCT01302912

USZ-OALs-Register

Details and patient eligibility

About

Imaging techniques have considerably improved over the last decades and ocular adnexal lymphomas (OALs) nowadays can be detected. As major advances in immunophenotyping and molecular diagnostics in histology have been achieved offering an accurate diagnosis, the investigators would like to introduce that surgical biopsy of an orbital lymphoma becomes crucial for the possibility of a correct diagnosis and proper treatment. As radiotherapy accomplished great preciseness as well and OALs respond excellently to radiation, this therapy should be the treatment of choice in local defined lymphomas instead of blind treatment with steroids. Radiation results in great local control rates of 85% to 100%

• Trial with surgical intervention

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria: - both genders

• >17 years of age
• underwent biopsy of an ocular adnexal lymphoma between 01/2006 and 12/2010 at the University Hospital Zurich, Division of Ophthalmology
• diagnosis histologically proven

Exclusion criteria:

• less than 18 years of age
• patient underwent no MRI before surgery (biopsy)