Maca in Healthy Subjects After Strenuous Endurance Exercise

Taipei Medical University

Status: Active, not recruiting

Conditions: Healthy

Treatments: Dietary Supplement: maca; Dietary Supplement: placebo

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT05779488

MOST110-2410-H-038-013 (Other Grant/Funding Number)

N202103118

Details and patient eligibility

About

The aim of this study is to investigate Lepidium meyenii (Maca) extract supplementation on exercise-induced responses of the biochemical, and physiological parameters.

Full description

Thirty healthy male participants were divided into Maca group (2.25 g of Maca extract, twice per day for 12 weeks) and placebo group (n = 15). All participants conducted a graded exercise test on treadmill to determine the maximal oxygen consumption (VO2max) before and after supplementation, and the speed equivalent to 70% VO2max was conducted for an exhaustive endurance exercise test by treadmill for 1 hours, followed by 90% VO2max until exhaustion.The time to exhaustion, peak oxygen consumption, maximal heart rate and average heart rate will be recorded during the exercise period. Venous blood samples will be drawn before, immediately after, 2-hour after, 4-hour after, and 24-hour after the exhaustive endurance exercise test. Data was analyzed by Two-way mixed design ANOVA.

Enrollment: 50 estimated patients

Sex: Male

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

The volunteers included have conditions as stated below :

1. male adult whose no history of cardiovascular, liver, kidney and diabetes disease
2. no acute sport injury
3. did not participated in any clinical trials or research in the last 3 months before our experiment
4. no supplements were taken during the experimental period
5. were requested to maintain their regular daily life style and avoid alcohol intake

Exclusion criteria

The volunteers were excluded if they have the situation stated below:

1. history of cardiovascular, liver, kidney and diabetes disease
2. acute sport injury
3. participated in any clinical trials or experimental research in the last 3 months before our experiment
4. taking supplement during the experimental period
5. did not maintain their regular eating habit or drink alcohol

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups, including a placebo group

maca group

Experimental group

Treatment:

Dietary Supplement: maca

Placebo group

Placebo Comparator group

Treatment:

Dietary Supplement: placebo