Machine Learning-Based Risk Profile Classification of Patients Undergoing Elective Heart Valve Surgery

Kepler University Hospital

Status: Completed

Conditions: Heart Valve Diseases; Surgery--Complications

Study type: Observational

Funder types: Other

Identifiers

NCT03724123

K-82-15

Details and patient eligibility

About

Machine learning methods potentially provide a highly accurate and detailed assessment of expected individual patient risk before elective cardiac surgery. Correct anticipation of this risk allows for improved counseling of patients and avoidance of possible complications. The investigators therefore investigate the benefit of modern machine learning methods in personalized risk prediction in patients undergoing elective heart valve surgery.

Full description

The investigators performe a monocentric retrospective study in patients who underwent elective heart valve surgery between January 1, 2008, and December 31, 2014 at our center. The investigators use random forests, artificial neural networks, and support vector machines to predict the 30-days mortality from a subset of demographic and preoperative parameters. Exclusion criteria were re-operation of the same patient, patients that needed anterograde cerebral perfusion due to aortic arch surgery, and patients with grown up congenital heart disease.

Enrollment: 2,229 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

* Patients who underwent heart valve surgery of any kind between 2008-01-01 and 2014-12-31 were included.

Exclusion criteria

• re-operation of the same patient
• patients that needed anterograde cerebral perfusion due to aortic arch surgery
• patients with grown-up congenital heart disease