Macular Function During Anti-VEGF Treatment (MAFAT)

Royal Liverpool University Hospital

Status: Unknown

Conditions: Age Related Macular Degeneration

Study type: Observational

Funder types: Other

Identifiers

NCT01023971

Trust R&D_3704

Details and patient eligibility

About

The purpose of this study is to determine the changes in macular function during anti-VEGF treatment for neovascular age-related macular degeneration.

Full description

Macular function will be investigated using visual acuity, contrast sensitivity, mfERG and microperimetry.

Enrollment: 40 estimated patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Neovascular AMD in first or second eyes
• angiographic signs of active subfoveal or juxtafoveal choroidal neovascularization (CNV)
• BCVA ≥35 ETDRS letters

Exclusion criteria

• Spherical equivalent ≥ ± 6 D
• Previous treatments for CNV in the studied eye

Trial design

40 participants in 2 patient groups

Group A

Description:

Patients investigated with mfERG and MP-1

Group B

Description:

Patients investigated by Laser Doppler Flowmetry