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MAGnesIum Alloy Scaffold for Coronary Artery Disease (MAGIC)

S

San Luigi Gonzaga Hospital

Status

Unknown

Conditions

Coronary Artery Disease
Myocardial Infarction

Treatments

Device: Scaffold

Study type

Observational

Funder types

Other

Identifiers

NCT04098042
001/2019

Details and patient eligibility

About

The retrospective study will investigate the clinical performance and long-term safety of scaffold implantation in a real world setting including high volume PCI centers in Italy

Full description

Coronary stents are the default devices for the treatment of coronary artery disease in percutaneous coronary intervention (PCI) according to existing guidelines. However, thrombosis and restenosis are still the main limitations of current permanent metallic stents. In contrast to Bare Metal Stents (BMSs), Drug Eluting Stents (DESs) have a reduced restenosis rate due to the presence of antiproliferative agents in the coating layer of the stent surface and reduced rate of repeat revascularisation. However, late and very late stent thrombosis remains the limitation of DES in spite of prolonged dual antiplatelet therapy. Bioabsorbable scaffolds have been introduced to overcome limitations of permanent metallic stents.

The aim of this observational retrospective study is to investigate the clinical performance and long-term safety of scaffold in a real world setting.

Institution involved in the present registry are high volume PCI centers. Operators have experience in PCI with bioresorbable scaffolds technology

The study organization is based on:

DATA SAFETY MONITORING BOARD (DSMB) All adverse events will be reported to the DSMB and reviewed on an on-going basis throughout the subject enrolment and follow-up period to ensure the safety of subjects enrolled in this study. In case of clinical events, coronary artery angiographies and percutaneous coronary interventions was reviewed by an independent core-lab.

Enrollment

175 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • subjects >18 years
  • Able to provide an informed consent
  • implantation of at least one scaffold

Exclusion criteria

  • inability to provide at least one year follow-up

Trial design

175 participants in 1 patient group

Scaffold
Description:
Patients receiving during PCI the implantation of at least one Magnesium Made Bioresorbable Scaffold "Magmaris"
Treatment:
Device: Scaffold

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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