ClinicalTrials.Veeva

Menu

Magnesium and Rotational Thromboelastometry (ROTEM) in Colorectal Cancer Surgery

Seoul National University logo

Seoul National University

Status

Completed

Conditions

Colorectal Cancer

Treatments

Drug: Magnesium Sulfate
Drug: Normal saline

Study type

Interventional

Funder types

Other

Identifiers

NCT01938300
Mg-ROTEM-colorectal ca

Details and patient eligibility

About

Magnesium sulphate is given to the patients during the colorectal cancer surgery under the hypothesis that it would attenuate the postoperative hypercoagulability. The investigators intend to characterize the changes of coagulation in colorectal cancer patients by using the point-of-care device after the infusion of magnesium sulphate.

Enrollment

44 patients

Sex

All

Ages

20 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • The patients undergoing a laparoscopic colorectal cancer surgery

Exclusion criteria

  • Renal disease
  • Hepatic disease
  • Neuromuscular disease
  • Coagulation disorder
  • Cardiopulmonary disease

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

44 participants in 2 patient groups, including a placebo group

Magnesium
Experimental group
Description:
Magnesium sulfate infusion during a operation period. Infusion regimen: 1. Bolus 50 mg/kg of magnesium sulfate in 100 ml normal saline over 15 minutes 2. Infusion 15 mg/kg/h of magnesium sulfate throughout the operation
Treatment:
Drug: Magnesium Sulfate
Control
Placebo Comparator group
Description:
administration of normal saline as a same volume of magnesium sulphate as a same method.
Treatment:
Drug: Normal saline

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems