Magnesium and TKA Pain

Seoul National University

Status: Unknown

Conditions: Pain

Treatments: Drug: Magnesium Sulfate

Study type: Interventional

Funder types: Other

Identifiers

NCT01945437

Mg_TKA

Details and patient eligibility

About

The hypothesis of this study is that in staged bilateral total knee arthroplasty (TKA, magnesium sulfate administered during the perioperative period of the first TKA may decrease pain after the second TKA. It is known that pain is greater in the second TKA than in the first. Therefore, we compared pain of the second TKA between the magnesium and control groups.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: American society of anesthesiologist physical status 1 - 2. patients scheduled to undergo staged bilateral TKA

Exclusion Criteria: American society of anesthesiologist physical status >3

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Control

Placebo Comparator group

Description:

Control group receive same volume of normal saline as in the magnesium group

magnesium

Experimental group

Description:

This group receive magnesium sulfate perioperatively.

Treatment:

Drug: Magnesium Sulfate