Magnesium As an Adjuvant Agent for Postoperative Pain

University Hospitals (UH)

Status and phase: Begins enrollment in 1 month; Phase 4

Conditions: Pain, Postoperative

Treatments: Drug: IV Magnesium Sulfate

Study type: Interventional

Funder types: Other

Identifiers

NCT05947760

STUDY20230720

Details and patient eligibility

About

Participants are being asked to participate in this research study because they have elected to undergo periacetabular osteotomy (PAO). This research study is looking at if using IV magnesium during surgery can help to reduce pain after surgery.

Enrollment: 64 estimated patients

Sex: All

Ages: 14 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing periacetabular osteotomy with or without adjuvant hip arthroscopy

Exclusion criteria

• illiterate or non-English speaking patients
• patients with 2nd or 3rd degree AV block
• patients with severe renal insufficiency
• patients with heart failure
• patients with bradycardia

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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64 participants in 2 patient groups

IV Magnesium Sulfate adjuvant group

Experimental group

Description:

Participants in this group will receive standard-of-care procedures intraoperatively and postoperatively along with IV magnesium sulfate for pain control.

Treatment:

Drug: IV Magnesium Sulfate

Control group

No Intervention group

Description:

Participants in this group will receive standard-of-care procedures intraoperatively and post-operatively for pain control.