Magnesium Injection Ensures Steroid Avoidance During Vaccine, Viremia or Immunocompromise

Salem Anaesthesia Pain Clinic

Status: Enrolling

Conditions: Steroid Metabolism Disorder

Treatments: Drug: Magnesium

Study type: Observational

Funder types: Other

Identifiers

NCT05862454

SalemAnes2022 Mg Steroid Avoid

Details and patient eligibility

About

Steroid injections are used for interventional pain management. However, their side-effect of immunosuppression may increase the risk of infections. Magnesium is an alternative anti-nociceptive injection that may be used instead of steroids.

Prospective observational study of patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant.

Full description

Corticosteroid injections are used for interventional pain management. The immunosuppression effect of steroid injection may increase the risk of infections. Magnesium is an alternative anti-nociceptive agent that may be used for interventional pain injection therapy, instead of steroids.

Prospective observational clinical study of pain clinic patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant. Data analyzed with IBM® SPSS® Statistics 25 (IBM Corp, Armonk, NY); using Student's t-test, ANOVA, Pearson Chi-square test, and regression analysis. P-value <0.05 is considered significant.

Enrollment: 150 estimated patients

Sex: All

Ages: 20 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• adult chronic pain patients
• previous interventional injection therapy
• consent for interventional injection therapy
• good treatment compliance
• regular sleep diary
• regular pain diary
• informed consent for diary review
• consent for clinical record quality assurance review

Exclusion criteria

• organ insufficiency
• cognitive disorder
• inability to provide consent
• major neuropsychiatric disorder
• unreliable diary
• poor treatment compliance
• previous adverse/allergic reactions to magnesium

Trial design

150 participants in 1 patient group

Adult chronic pain patients

Description:

Cohort of adult chronic pain patients, undergoing interventional injection therapy for pain management at a Canadian pain clinic

Treatment:

Drug: Magnesium