Magnesium Supplementation in Type II Diabetes

Protina Pharmazeutische GmbH

Status

Completed

Conditions

Effect of Magnesium in Diabetes

Treatments

Dietary Supplement: Placebo

Dietary Supplement: Magnesium citrate

Study type

Interventional

Funder types

Industry

Identifiers

NCT03002545

DiaMag 2017

Details and patient eligibility

About

This study aims to determine how a 12-week magnesium supplementation with 400 mg magnesium from organic magnesium citrate affects blood glucose control and insulin resistance within patients with type 2 diabetes (HbA1c> 6%) and how the expression of certain Mg-sensitive transporting genes is affected .

Full description

The examinations are carried out in 50 subjects aged 20-80 years with existing type 2 diabetes (HbA1c> 6%). The target parameters are determined in the blood. Blood sampling takes place at confinement, after 6 weeks and at the end of the study (week 12). In addition, blood pressure is determined and general health condition of each subject is recorded by a standardized questionnaire (SF-36).

Enrollment

50 patients

Sex

All

Ages

20 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Type II Diabetics (HbA1c > 6%)

Exclusion criteria

pregnancy, lactation
persons with severe renal impairment (glomerular filtration rate <30 ml / min)
use of insulin, oral antidiabetic drugs, diuretics, antacids or proton pump inhibitors within 4 weeks prior to study start and during the study
intake of vitamin supplements, dietary supplements, mineral products or possibly enriched foods containing Magnesium within 4 weeks before study start and during the study