Magnetic Activated Cell Sorting in Artificial Insemination With Donor Sperm (MACSIAD)

IVI Sevilla

Status: Completed

Conditions: Infertility

Treatments: Other: MACS technique

Study type: Interventional

Funder types: Other

Identifiers

NCT03659812

IVISEV-006-IAD

Details and patient eligibility

About

The aim of this study is to analyse the efficacy of MACS technique for the selection of spermatozoa and its effects on implantation, pregnancy and miscarriage rate. This study will be performed by two IVI clinics (IVI Sevilla and IVI Madrid) with the purpose of finding new techniques that allow us to better select spermatozoa and improve the results of assisted reproduction techniques.

Enrollment: 130 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Women who undergo artificial insemination with donor sperm
• Signing an informed consent form to participate in the study

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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130 participants in 2 patient groups

MACS is applied to the sperm sample

Experimental group

Description:

Previous to the AID technique, the sperm sample undergoes capacitation through Percoll density gradient and MACS

Treatment:

Other: MACS technique

MACS is not applied to the sperm sample

No Intervention group

Description:

Previous to the AID technique, MACS only undergoes capacitation through Percoll density gradient, but not MACS technique