Magnetic Nanoparticle Sperm Separation for Teratozoospermia Male and Women Older Than 35 Years

Ibn Sina Hospital

Status: Completed

Conditions: Infertility

Treatments: Other: Sperm preparation for ICSI

Study type: Interventional

Funder types: Other

Identifiers

NCT03666364

IbnSina-MNP

Details and patient eligibility

About

Women over 35 years old are likely to suffer from impaired oocyte repair capacity. Teratozoospermia is a condition reflects morphological affection of sperm. These spermatozoa would add an extra burden on the oocyte after ICSI. Whether selecting mature sperm by magnetic nanoparticle protocol would provide a more competent sperm to a likely affected oocyte would improve ICSI outcomes is the question of this research.

Enrollment: 1,400 patients

Sex: Female

Ages: 35 to 42 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• women indicated for ICSI but with teratozoospermia

Exclusion criteria

• Women not failing in this group

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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1,400 participants in 2 patient groups

Magnetic nanoparticle selection for teratozoospermia

Experimental group

Treatment:

Other: Sperm preparation for ICSI

Density gradient centrifugation for teratozoospermia

No Intervention group