Magnetic Prefrontal Stimulation for Studying the Role of the Cortex in High-level Cognition Processes and Reward System

Hadassah Medical Center

Status and phase: Completed; Early Phase 1

Conditions: Healthy Volunteers

Treatments: Device: TMS

Study type: Interventional

Funder types: Other

Identifiers

NCT00912522

0116-09-HMO-CTIL

Details and patient eligibility

About

The investigators intend to study the role of the cortex in high- level cognition processes and sensory adaptation, by the use of non-invasive Transcranial Magnetic stimulation and various cognitive tests.

Enrollment: 91 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy men and women, age of 18-60
• answered negatively to questions of TMS safety questionnaire
• signed and declared about their agreement to participate in the study
• hebrew speaker

Exclusion criteria

• self history of significant mental disorder
• self history or first-degree relatives history of epilepsy

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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91 participants in 5 patient groups

LT PFC HIGH FREQ TMS

Active Comparator group

Treatment:

Device: TMS

LT PFC LOW FREQ TMS

Active Comparator group

Treatment:

Device: TMS

RT PFC HIGH FREQ TMS

Active Comparator group

Treatment:

Device: TMS

RT PFC LOW FREQ TMS

Active Comparator group

Treatment:

Device: TMS

SHAM STIMULATION

Sham Comparator group

Treatment:

Device: TMS