Magnetic Resonance Imaging in Subjects With Gouty Tophi

Takeda

Status: Completed

Conditions: Hyperuricemia; Gout

Treatments: Procedure: MRI

Study type: Observational

Funder types: Industry

Identifiers

NCT00174954

U1111-1113-9856 (Registry Identifier)

TMX-01-013

Details and patient eligibility

About

The purpose of this study is to determine the reproducibility of Magnetic Resonance Imaging (MRI) in the quantitative assessment of tophus volume.

Full description

This is a multi-center, validation study of MRI in the quantitative assessment of gouty tophi. Subjects with palpable gouty tophi (confirmed by aspiration of the tophus) in select anatomical sites (foot, hand or elbow) will undergo pre- and post contrast MRI on two occasions separated by 5 to 10 days. This study will consist of up to 4 study visits.

Enrollment: 32 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects with gout and at least one tophi.

Exclusion criteria

• Unable to undergo MRI.

Trial design

32 participants in 1 patient group

1

Description:

Volumes/measurements of tophi determined by serial MRIs

Treatment:

Procedure: MRI