Magnetic Resonance Imaging (MRI) Study of the Hippocampus After Infarction in the Territory of the Middle Cerebral Artery

Huazhong University of Science and Technology

Status: Unknown

Conditions: Ischemic Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT00867581

30725019-2

Details and patient eligibility

About

The purpose of this study is to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Full description

40 patients with middle cerebral artery infarction and 40 healthy volunteers will be observed. All of them will receive MRI scan and the assessment of the neuropsychological function (MMSE, AVLT, HAMD) intending to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Enrollment: 80 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of middle cerebral artery infarction
• At least six months from the stroke
• Must be able to measure his(her) neuropsychologic function (by MMSE, AVLT)

Exclusion criteria

• Unable to undergo examinations due to disturbances of consciousness or medical conditions
• Severe dementia, apraxia, disturbances of sensation or perception
• Serious complications including severe heart failure, hepatic dysfunction, renal insufficiency,or shock
• Parkinson's disease, malignant tumor, autoimmune diseases

Trial design

80 participants in 2 patient groups

1

Description:

chronic-stage patients after infarction in the territory of unilateral middle cerebral artery

2

Description:

age, sex and risk factor matched volunteers without ischemic stroke