Magnetic Resonance Imaging of Cognitive Deficits in the Brain of Individuals With Spinal Cord Injury (SCI_Cog)

Swiss Paraplegic Research, Nottwil

Status

Completed

Conditions

Spinal Cord Injury

Study type

Observational

Funder types

NETWORK

Identifiers

NCT06309888

2023-18

Details and patient eligibility

About

In the case of spinal cord injury, rehabilitation is particularly focused on motor skills. Non-motor impairments such as thinking difficulties did not receive a lot of attention to date.

In this research project, the investigators want to find out how thinking difficulties become noticeable in the brain with spinal cord injury.

Participation procedure: Participants who take part will be asked to come to an examination once. The duration of the examination is between 2 and 2.5 hours (including around 55 minutes in the magnetic resonance imaging scanner, including preparation and follow-up).

Enrollment

54 patients

Sex

All

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria (with and without spinal cord injury):

Male or Female
Age between 18 and 60
German native speaker
Normal or corrected-to-normal visual acuity

Additional inclusion criteria (spinal cord injury only):

A diagnosis of traumatic spinal cord injury (SCI)
Time since injury 12 months or longer
American Spinal Injury Association Impairment Scale (AIS) grade A, B, C and D

Exclusion criteria (with and without spinal cord injury):

Contraindication for magnetic resonance imaging examinations (e.g., cardiac pacemaker etc.)
Pregnancy
Diagnosis of other psychiatric or neurological disorders (including tumor in the central nervous system)
Alcohol and/or drug abuse
Confirmed diagnosis of traumatic brain injury
Insufficient hand function (not able to hold a pen due to the restricted motor abilities)