Magnetic Resonance (MR) Imaging in the Post Operative Follow-up of Cholesteatoma in Children

Public Assistance-Hospitals of Marseille (AP-HM)

Status: Completed

Conditions: Cholesteatoma

Treatments: Other: MR Imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT00682409

2007-22

2007-A00743-50

Details and patient eligibility

About

Classical imaging techniques are inaccurate to detect residual cholesteatoma. The aim of our study is to evaluate the value of diffusion-weighted MR imaging and delayed contrast enhanced T1 weighted spin-echo sequences in the detection of residual cholesteatoma in children, in a large serie of surgically verified cases.

Full description

Classical imaging techniques are inaccurate to detect residual cholesteatoma. Thin-section CT detects that the postoperative cavity is filled with a soft tissue mass. Classical MR imaging (T2 and T1 weighted spin-echo sequences) can not provide additionnal information about the nature of this filling : cholesteatoma, granulation or fibrous tissue.

Enrollment: 37 patients

Sex: All

Ages: 5 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female or male child enters 5 and 18 years
• Child having benefited from a surgical operation for cholesteatoma of the average ear acquired or congenital, one-sided or bilateral
• Child for whom an additional operating time is indicated
• Child without contraindication in the MRI
• Child having signed a enlightened assent
• Child among whom the parents or the legal representatives signed a enlightened assent

Exclusion criteria

• Child of less than 5 years old and more than 18 years
• Child presenting a chronic renal insufficiency
• Child for whom an additional operating time is not indicated
• Child having a contraindication in the MRI
• Child not having signed the assent or the parents of which did not sign the assent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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37 participants in 1 patient group

1

Other group

Description:

Analysis of the value of the imaging of distribution and the late sequence to differentiate the cholesteatoma of the fibrosis in the follow-up operating post at the child

Treatment:

Other: MR Imaging