Magnetic Resonance (MR) in Asthmatic Patients

University Health Network, Toronto

Status and phase: Terminated; Phase 1

Conditions: Asthma

Treatments: Device: magnetic resonance imaging (MRI) of the thorax

Study type: Interventional

Funder types: Other

Identifiers

NCT00188487

05-0174

Details and patient eligibility

About

Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.

Full description

A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All asthmatic patients are eligible.

Exclusion criteria

• Patients in whom MRI is contraindicated

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)