Magnifying NBI Endoscopy for Gastric Condition

Soon Chun Hyang University

Status: Completed

Conditions: Gastritis H Pylori

Treatments: Other: Magnifying narrow-band imaging endoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT04489030

SCH-NBI endoscopy

Details and patient eligibility

About

Recently, the improved resolution with standard endoscopy allows the close observation of highly inflamed gastric mucosa without a magnifying view. In a previous study, the investigators established the endoscopic classification of H. pylori-infected stomach by non-magnifying standard endoscopy. One normal RAC pattern and three types of abnormal patterns were observed. Overall diagnostic accuracy for predicting H. pylori-infection was 91.6%. However, there is no comparison study predicting H. pylori-infection and precancerous gastric lesions between standard and magnifying endoscopy.

Full description

The investigators aimed to evaluate the diagnostic efficacies of non-magnifying standard endoscopy for predicting H. pylori-infection status and precancerous gastric conditions, compared to magnifying NBI endoscopy

Enrollment: 254 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Gastroscopy can be performed
• H. pylori test and pathological analysis can be performed

Exclusion criteria

• Age < 20 or > 70 years
• Anemia (serum hemoglobin level < 10 g/dL)
• Severe systemic disease
• Advanced chronic liver disease
• Use of certain medications, including proton pump inhibitors, H2- receptor antagonists, or antibiotics
• History of H. pylori eradication
• History of gastric surgery
• Recent history of upper gastrointestinal bleeding