Main Branch Versus Side Branch Ostial Lesion

Seoul National University

Status: Completed

Conditions: Coronary Artery Stenosis

Treatments: Device: Fractional flow reserve; Device: IVUS

Study type: Observational

Funder types: Other

Identifiers

NCT01335659

Bif_3

Details and patient eligibility

About

The investigators studied the relations between coronary angiography (CAG), intravascular ultrasound (IVUS) and fractional flow reserve (FFR) in coronary ostial lesions.

Full description

Angiographic evaluation for ostial lesions is reported to be inaccurate in the assessment of the functional and clinical significance of a lesion. The investigators studied the relations between coronary angiography (CAG), intravascular ultrasound (IVUS) and fractional flow reserve (FFR) in coronary ostial lesions.

Enrollment: 77 patients

Sex: All

Ages: 21 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 21-85
• Presence of at least one obstructive coronary artery stenosis at coronary ostium as defined by:
• Previous catheterization with any coronary ostium lesion 50% or greater
• Ability and Willingness to provide informed consent
• Ability and Willingness to perform required follow up procedures

Exclusion criteria

• History of coronary artery bypass graft surgery
• left main coronary ostial lesion
• significant stenosis at proximal or distal part of coronary ostium lesion
• ostial lesion related to infarcton
• Creatinine>1.6 mg/dL or GFR<30 pre-procedure per institutional standards
• Ejection fraction lower than 40%
• Known Pregnancy
• Arrhythmia
• Contrast agent allergy that cannot be adequately premedicated
• Patient not a candidate for IVUS and FFR
• Inability or unwillingness to provide informed consent
• Inability or unwillingness to perform required follow up procedures

Trial design

77 participants in 1 patient group

ostial lesion

Description:

ostial lesion will be evaluated by IVUS and FFR

Treatment:

Device: IVUS

Device: Fractional flow reserve