Maintenance Transcranial Electrical Stimulation for Depression

The University of New South Wales

Status

Completed

Conditions

Major Depressive Disorder

Bipolar Disorder

Treatments

Device: Transcranial electrical stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT01890356

HC12499

Details and patient eligibility

About

Transcranial electrical stimulation (TES) techniques offer a novel treatment approach for depression and have shown promising efficacy. However, there is no published data to date on their effectiveness as a maintenance treatment. This study will investigate ways of using TES as a maintenance treatment to prevent relapse in depression.

Enrollment

25 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All participants will be ≥ 18 years old.
Participants must have experienced a significant clinical response, defined as ≥ 50% decrease from baseline scores on the Montgomery Asberg Depression Rating Scale (MADRS).

Exclusion criteria

Inadequate response to acute trial of TES.
Suicidality.
Clinically defined neurological disorder or insult.
Metal in the cranium, skull defects, or skin lesions on scalp (cuts, abrasions, rash) at proposed electrode sites.
Pregnancy (women of childbearing age will be asked to undergo a urine pregnancy test prior to starting the study).
Concurrent long acting benzodiazepines, ritalin or dexamphetamine medication.
Treatment for depression is changed during months 3-9 of the trial.