Male Supplements for Sperm Quality and Aging

Kaohsiung Veterans General Hospital

Status: Enrolling

Conditions: Unrecognized Condition

Treatments: Dietary Supplement: Male supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT06339996

KSVGH24-CT1-10

Details and patient eligibility

About

This study investigates the effects of a new supplement on sperm quality in men with poor sperm quality. Fifty patients will receive the supplement for three months, followed by semen analysis and assessment of sperm aging and mitochondrial function. Changes in sexual function and aging symptoms will also be evaluated.

Full description

Due to modern lifestyle factors such as high work pressure, stressful routines, and environmental pollution, there has been a significant decline in sperm quality among men, potentially leading to infertility. In response, various supplements have emerged claiming to enhance sperm quality. This prospective investigation aims to determine the efficacy of a new supplement in improving sperm quality among patients with poor sperm quality. The study will enroll 50 patients undergoing semen analysis at our reproductive center, administering the supplement over a three-month treatment period to those identified with poor sperm quality. Subsequent semen analysis will be conducted, alongside assessments of sperm mitochondrial metabolic function before and after supplement administration. Sexual function and aging symptoms will also be evaluated using the International Index of Erectile Function (IIEF-5) and the Aging Males Symptoms Scale (AMS) before and after the supplementation period. The study aims to compare differences in semen analysis, sperm mitochondrial metabolic function, sexual function, and aging symptoms before and after supplementation.

Enrollment: 50 estimated patients

Sex: Male

Ages: 30 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Not meet the criteria of the 6th edition of the WHO manual for human semen analysis
• BMI:18-30 kg/m2

Exclusion criteria

• Azoospermia
• Varicocele
• Chromosome anomaly
• Malignancy
• Using hormone therapy or supplements in recent 3 months

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Male dietary supplement

Experimental group

Description:

Patients received male supplements for a three-month treatment period

Treatment:

Dietary Supplement: Male supplement