Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide

Ankara City Hospital

Status and phase: Completed; Phase 4

Conditions: Acute Gastroenteritis; Abdominal Pain

Treatments: Drug: Hyoscine N Butylbromide; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT04682860

Çağdaş Yıldırım

Details and patient eligibility

About

One of the most common complaints of admission to the emergency room is gastroenteritis. One of the most common complaints in acute gastroenteritis is abdominal pain. The aim of our study is to investigate whether hyoscine butylbromide used within the indication has an effect on abdominal pain due to acute gastroenteritis. The main purpose of our study is to reduce the pain of the patient at 30th and 60th minutes compared to 0th minute.

Enrollment: 50 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with watery stools starting in the last 2 weeks and 3 times in 24 hours and abdominal pain

Exclusion criteria

• Peritonitis
• Hemodynamic instability
• Pregnancy
• Inability to give consent
• Medication given in the emergency room before being included in the study
• Taking pain medication within 4 hours
• Diabetes Mellitus and other neuropathic diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

In the placebo arm, patients will be slowly injected with 2 ml of normal saline within 30 seconds

Treatment:

Other: Placebo

Hyoscine N butylbromide

Active Comparator group

Description:

In the treatment arm, the patient will be injected intravenously with 1ml 20 mg of Hyoscine butylbromide and 1 ml of normal saline intravenously within 30 seconds.

Treatment:

Drug: Hyoscine N Butylbromide