Management of Adrenal Emergency in Germany (MAdEy)

Wuerzburg University Hospital

Status: Completed

Conditions: Adrenal Insufficiency

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT03426332

MAdEy-Study

Details and patient eligibility

About

The management of adrenal crisis is often problematic and the time to adequate treatment is frequently delayed.The aim of the study is to evaluate the management of adrenal emergencies requiring parenteral glucocorticoid treatment by a prospective multicenter study in patients with chronic adrenal insufficiency.

Full description

Despite established hormone replacement therapy, patients with chronic adrenal insufficiency (AI) are at risk of suffering from adrenal crisis (AC). Further data suggests that the management of AC is often problematic and the time to adequate treatment is frequently delayed.The aim of the study is to evaluate the management of adrenal emergencies (AE) requiring parenteral glucocorticoid (GC) treatment by a prospective multicenter study.

Patients with chronic AI receive a questionnaire on the management of emergency situations, which had to be completed and sent back in case of an emergency requiring parenteral GC administration. Furthermore, patients were contacted by phone in case of a missing response every six months.

Enrollment: 150 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• Documented chronic adrenal insufficiency
• Established corticosteroid replacement therapy
• Written informed consent

Exclusion criteria

• Age <18 years