Management of Anticoagulants and Antithrombotics in Patients With CSDH (THERCA)

University Hospital of Ferrara

Status: Enrolling

Conditions: Thromboembolic Stroke; Anticoagulant-induced Bleeding; Chronic Subdural Hematoma; Cardiovascular Stroke

Treatments: Procedure: CSDH evacuation

Study type: Observational

Funder types: Other

Identifiers

NCT05079295

1102/2020/Oss/AOUFe

Details and patient eligibility

About

Primary objective of the study will be to compare, up to 6 months after surgery, number of relapses (post operative re-bleeding) or intracerebral hemorrhage (others than subdural hematomas) and thromboembolic or cardiovascular ischemic events, in patients undergoing surgery for chronic subdural hematoma (CSDH). These data will be correlated to the suspension or not of antithrombotics or anticoagulants before surgery or their re-introduction after surgery.

Enrollment: 400 estimated patients

Sex: All

Ages: 18 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years old
• Informed consent
• Evidence of CSDH which needs surgery
• patients taking antithrombotics or anticoagulants

Exclusion criteria

• previous surgery for CSDH

Trial design

400 participants in 2 patient groups

Group 1

Description:

Patients taking anticoagulants or antithrombotics

Treatment:

Procedure: CSDH evacuation

Group 2

Description:

Controls

Treatment:

Procedure: CSDH evacuation