Management of Non Convulsive Status Epilepticus

Assiut University

Status: Unknown

Conditions: Status Epilepticus

Treatments: Other: cross sectional

Study type: Observational

Funder types: Other

Identifiers

NCT03245099

MONCSE

Details and patient eligibility

About

Non convulsive status epilepticus is a persistent change in behavioural and or mental process from baseline associated with continuous epileptiform activity in electroencephalograph,it occur in about 50 percent in patients with coma and convulsions and in 8-13 percent in intensive care unit patients

Full description

Early recognition and treatment of non convulsive status epilepticus are essential to optimize response to treatment and to prevent neurological sequelae, over diagnosis and aggressive use of anticonvulsants can contribute to morbidity and mortality.It displays great diversity in response to anticonvulsants,therefore treatment in intensive care units is required for selected cases .The aetiology and clinical forms are strong predictors for the overall prognosis.Treatment is poorly understood and follows the standard regimen for convulsive status epilepticus

Enrollment: 100 estimated patients

Sex: All

Ages: 12 months to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who have generalized tonic colonic convulsions and prolonged post ictal state more than 30 minutes
• patients presented with un explained psychic or speech disorder
• patients presented with stupor or confusion
• Patients presented with un explained coma

Exclusion criteria

• patients with progressive neurological disease
• Patients with severe cerebral anoxia
• Patients with liver or hepatic impairment