Management of Patients on Long Term Anticoagulation Therapy Undergoing a Primary Total Hip of Knee Replacement (ADELC)

Association pour le Développement et l'Enseignement de la Chirurgie Réparatrice et Orthopédique

Status: Unknown

Conditions: Postoperative Complications

Treatments: Drug: anticoagulation

Study type: Observational

Funder types: Other

Identifiers

NCT02714673

ADECRO

Details and patient eligibility

About

It is a multicenter, prospective, observational study of standard care. This study analyses the care of patients on long term effective anticoagulation therapy (ADELC) during a primary hip or knee arthroplasty.

The objectives of the study are to:

1. Identify clinical practices set up for patient care
2. Assess the type and the frequency of perioperative complications
3. Look for factors, related to patients or treatments, associated with the occurrence of these complications.

The main objective is to estimate the risks, adjusted and not, of postoperative complications associated to a long term anticoagulation by comparing patients under anticoagulation to a control group of patients having the same interventions but who are not under anticoagulation.

Enrollment: 600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult ≥ 18 years
• Programmed for primary hip or knee arthroplasty.
• Effective dose of anticoagulant drugs intake for more than 1 month with the intention to resume it after the intervention for ADELC cohort; no effective dose of anticoagulant drugs intake for the control cohort.

Exclusion criteria

• Patient non opposition

Trial design

600 participants in 2 patient groups

ADELC

Description:

Cohort of patients on long term anticoagulation and undergoing a primary hip or knee replacement.

Treatment:

Drug: anticoagulation

CONTROL

Description:

Cohort of patients not on long term anticoagulation and undergoing a primary hip or knee replacement.