Management of Postoperative Pain After Total Hip Arthroplasty

Chang Gung Medical Foundation

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Osteoarthritis of Hip

Treatments: Drug: Bupivacaine; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01040273

THA

Details and patient eligibility

About

Orthopedic surgery is reportedly among the most painful surgical procedures. Surgical damage following major orthopedic surgery often involves a large, deep incision with considerable tissue dissection and muscle, bone, and vascular exposure. Post-operative pain after such surgery is exacerbated on movement or by reflex spasms of the muscles, which may delay mobilization, reduce satisfaction, prolong hospitalization, and possibly increase medical costs.

We design a prospective randomized study for postoperative pain control following total hip arthroplasty.

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diagnosed for surgery of osteoarthritis of hip
• ability to tolerate surgery under general anesthesia.

Exclusion criteria

• refusal or the lack of mental ability to provide informed consent
• neuropathic pain or sensory disorders in the leg requiring surgery
• previous surgery of the hip joint
• coagulation abnormalities
• severe renal or hepatic impairment
• chronic opioid users
• known history of intolerance to the drugs used in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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0 participants in 2 patient groups, including a placebo group

Experiment

Experimental group

Description:

Anesthetics intraarticular injection

Treatment:

Drug: Bupivacaine

Placebo

Placebo Comparator group

Description:

saline intraarticular injection

Treatment:

Drug: Placebo