Management of Supraventricular Tachycardias in Children

Paris Cardiovascular Research Center (Inserm U970)

Status: Completed

Conditions: Children; Supraventricular Arrhythmias; Management

Treatments: Other: Management of children with supraventricular tachycardias

Study type: Observational

Funder types: Other

Identifiers

NCT07291544

WALDMANN202501

Details and patient eligibility

About

Background

Supraventricular tachycardias (SVTs) are the most common arrhythmic events in children, with an estimated incidence of 13 per 100,000 per year before the age of 18. Few large patient cohorts have been reported, as most published studies are single-center. Large-scale studies come from medico-administrative databases, which lack the granularity needed for detailed analysis of outcomes according to the therapies used and the type of SVT.

Furthermore, although a large proportion of neonatal SVTs do not recur (spontaneous resolution of the accessory pathway), there are limited comparative data on the effectiveness of antiarrhythmic therapies specifically in children after the age of 1 year. Management therefore varies greatly, in part because current guidelines propose different therapeutic options based on low-level evidence.

Objectives:

• Describe the management of SVTs (antiarrhythmic therapies and catheter ablation) in children in France
• Compare the effectiveness of different antiarrhythmic treatments according to age (<1 year and >1 year) and type of SVT
• Analyze the incidence of adverse events and complications associated with antiarrhythmic treatments and catheter ablation

Enrollment: 1,400 patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age <18 years at the time of the first documented supraventricular tachycardia episode

Exclusion criteria

• Early postoperative supraventricular tachycardia (<30 days)
• Age ≥18 years at the first documented supraventricular tachycardia episode
• Fetal tachycardias without postnatal recurrence
• Atrial extrasystoles without sustained runs (<30 seconds)