Management of Symptomatic Uterine Fibroids in Pregnancy by Laparotomic Myomectomy: a Prospective Cohort Study (LPTM-UFs-P)

University of Palermo

Status: Enrolling

Conditions: Uterine Fibroid; Pregnancy Related

Treatments: Procedure: Laparotomic myomectomy during pregnancy

Study type: Observational

Funder types: Other

Identifiers

NCT06009562

LPTM-S-UFs-Pregancy

Details and patient eligibility

About

The frequency of women presenting with a combination of uterine fibroids and pregnancy is in-creasing nowadays. Uterine fibroids in pregnancy are an unfavorable condition in themselves and being reactive to hormonal stimuli, tending to grow, can generate symptoms of different lev-els of severity. Obstetrics and gynecologists are increasingly faced with the problem of clarifying the management tactics of pregnant patients with symptomatic fibroids, who may see their preg-nancy put at risk by these masses.

Enrollment: 28 estimated patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• The large and giant size of UFs, which prevent the proper continuation of pregnancy and/or occupy the entire small and large pelvis, as well as invade and/or occupy the abdominal cavity.
• Circulatory disorders, evidenced by necrosis of the UFs.
• Atypical localization of UFs (cervical, isthmic, intraligamentary, etc.), which caused pelvic organ dysfunction (dysuric phenomena, tenesmus, impediment to the act of defecation, pelvic pain).

Exclusion criteria

• Refusal of LPTM by the patient.
• Absence of urgent indication for LPTM during pregnancy.